Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher.
Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?
Some links on this page may take you to non-federal websites. Their policies may differ from this site.
-
Free, publicly-accessible full text available July 4, 2026
-
Lipstick, a widely used cosmetic, is an ideal substrate for colorimetric biosensors due to its direct contact with saliva, nutrition, frequent use, color range, and discrete nature. This paper presents ChromaLipSense, the design of a lipstick that seamlessly embeds a colorimetric biosensor whose colors change in response to pH levels. ChromaLipSense addresses limitations in existing biosensor technologies, such as portable monitors and transdermal patches, which often pose challenges related to attachment, invasiveness, and electronic requirements. Saliva is suitable for biosensing due to its transparency, regenerability, and health-indicative composition. The main contributions include biosensing lipstick form factor, DIY fabrication process using skin-safe products, design considerations for these devices, and color detection system for biosensor identification and its technical evaluation. ChromaLipSense extends the concept of the ‘Biocosmetic Interface’ which merges cosmetics with biotechnology for chemical analysis to access previously unexplored bodily fluids.more » « lessFree, publicly-accessible full text available June 26, 2026
-
Free, publicly-accessible full text available April 25, 2026
-
Feline urine provides valuable insights into an animal's well-being. However, professional veterinary urine analysis can be invasive, costly, and infrequent. Electrochemical biosensors, widely used in medical diagnosis, environmental monitoring, food quality control, and drug discovery, offer a promising solution for sensing analytes in feline urine. This paper introduces the "Feline Biofluids IoT Hub" concept that aims at making previously inaccessible biological data in pets' fluids visible and integrates biofluid sensing with an Internet of Things (IoT) system to enhace comprehensive animal health monitoring. To implement that concept, our project GluCAT includes a biosensing litter box and an activity sensing mat to facilitate the care of diabetic cats. Chronoamperometic data is capture from the electrochemical biosensor using a potentiostat and send to a database via Wi-Fi, providing data visualization through a mobile application. We present electrochemical biosensor tests across five glucose levels. We compare results from feline urine samples with laboratory-grade tests. Furthermore, we share insights from a real-world user study involving a cat interacting with GluCAT for over 50 hours. We envision our project enabling the monitoring of various illnesses by detecting analytes like pH, sodium, and glucose in feline urine using electrochemical biosensors, complemented by data from pet-oriented IoT devices measuring water intake, activity, weight, and food consumption.more » « less
-
Feline urine provides valuable information on an animal’s wellbeing, but professional veterinary collection and analysis of urine samples can be intrusive, costly, and infrequent. Electrochemical biosensors recognize biological elements such as pH, glucose and sodium, and have numerous applications, including in medical diagnosis, environmental monitoring, food quality control and drug discovery. This paper presents cirCAT: PURRtentio, a litter box system that uses a electrochemical biosensor to monitor analytes in feline urine. We provide the implementation process of the system that consists of a DIY three-electrode biosensor, a potentiostat, a microcontroller, a ToF sensor and a mobile application. A rinsing mechanism is also included to extend the lifespan of the sensors. The system was tested using three separate electrochemistry tests to ensure accuracy, reliability, and applicability. We prepared and compared electrochemical biosensors with different conductive materials for Do-It-Yourself (DIY) electrodes. The second test compared PURRtentio against an industry-grade potentiostat. The third test compared our system against current veterinary standards for chemical analysis using feline’s urine samples. Additionally, we conducted a case study with a cat using PURRtentio for 72 hours. Finally, with results from these research and another series of interviews we did with veterinarian experts, we provide implications and future directions of this technology. PURRtentio presents an innovative and non-invasive means to consistently monitor chemistry elements in feline urine, potentially allowing for early detection and management of cat’s health conditions.more » « less
-
This paper presents BioSparks, a wearable device that detects glucose levels in sweat through electrochemical biosensors crafted with traditional jewelry techniques. Unlike conventional biosensors that are disposed of after use, BioSparks employs a repurposing method, allowing for the reuse of discarded electrodes within the jewelry’s chain, as pendants or earrings. It incorporates interchangeable electrodes that facilitates their replacement after timelife. The modular design enables the wearable to be placed on various body parts, including the neck, wrist and waist. The paper outlines our design considerations for Wearability Factors for Jewelry Biosensors, and the fabrication process combining traditional jewelry techniques and electromistry. Our technical evaluation shows the performance of our biosensor under ten different glucose concentrations.more » « less
-
Traditional collection and analysis of feline urine samples for health monitoring are invasive, expensive, and infrequent. This paper introduces PURRtentio, a novel litter box system utilizing an electrochemical biosensor to monitor analytes in feline urine. The system comprises a DIY biosensor, potentiostat, microcontroller, distance sensor, and mobile application. Performance validation compared PURRtentio with an industry-grade potentiostat. PURRtentio presents an innovative and non-invasive approach for consistent monitoring of chemistry elements in feline urine, enabling early detection and management of cat’s health conditions. This technology has the potential to revolutionize feline health monitoring, providing a solution for veterinarians and pet owners.more » « less
An official website of the United States government
